Major Science FS-100L SIP Fermentation System (100L, 170Wx130Dx245H cm)

Capacity: 100L  

Total volume: 120L  

Working volume: 100L  

Dimension: Approx. 170Wx130Dx245H cm, Open distance of headplate lift : 60 cm)

Vessel and jacket maximum working pressure: 3 bar (43.5 psig) / 3 bar (43.5 psig)

Type: Double layered fully enclosed capsule-type tank, with an outer temperature protective layer

Material: Direct contact to medium - 316L stainless steel; all others - 304 stainless steel

Surface finish: Interior polish ≦ 25 Ra/in (0.6 μm) Mechanical polishing; Electropolish optional

Exterior polish: ≦ 32 Ra/in (0.8 μm) Mechanical polishing; Electropolish optional

Ports: Ports designed according to user requirements

Piping and valve materials:
Parts that directly contact with the product/medium uses 316L stainless steel (≤25 Ra/in) internal polished tubing (BPE standard) :

A. Internal EP polished diaphragm type pneumatic valve and manual valve (BPE standard)

B. Tubing all welded with orbital welding

C. Vessel bottom drain uses a diaphragm valve, to minimize dead volume

D. Piping designed for ease of transfer to scale up

(can be used as a seed fermentation system)

or downstream process

Parts that do not directly contact product/medium

A. Constructed with 304 stainless steel

Controller 12” color industrial touch screen

* User-friendly, graphical control interface

* Includes secure user accounts, with different levels of access

* Use stainless-steel controller cabinet (100 L and above only)

* Modularized and standardized design (Module Skid):

ergonomically designed according to height, ease of vessel clean up, and ease of extraction in relation to vessel bottom valve

* Includes maintenance page with system diagnostics

* All programmed setting values are automatically stored into the built-in memory; the settings will not be lost in case of power outage/interruption.

When power is restored, the interrupted process will automatically resumed

Setting
* Automated sterilization process

* Automated fermentation program

DO
* 0-200%, Control range: 0-100%, adjustable

* Software electrode calibration, with automatic temperature compensation function

* Includes one set of side-inserted stainless steel autoclavable DO electrode

* DO Stat features with intelligent feeding

pH
* PID control with adjustable deadband

* Control range 0 to 14 (2-12 for maximum precision), resolution: 0.01 pH

* Calibration function with automatic temperature compensation function

* Includes one set of side-inserted, autoclavable pH probe with stainless steel housing

* pH Stat features with intelligent feeding

Pump
* Built-in peristaltic pumps

* Each feeding pump can run adjustable 15-step program

* Each pump can be adjusted for speed, forward and backward direction, and manual or automatic mode

* Each of the four peristaltic pumps can be designated for different functions: acid pump, base pump, antifoam pump, or substrate feeding pump

* Optional fifth and six peristaltic pump available

Temperature
* Vessel temperature is measured with a side-inserted PT-100 temperature probe and maintained using PID control.

* Control range: 0-130°C, ±0.1°C. Operational range up to 0-60°C.

Agitation
* Manual or automatic control of agitation speed

* 15-step program to change speed, or use DO cascade control

Air supply and exhaust
Gas supply and dehumidifer: uses in-house air compressor or air dehumidifier

* Includes re-useable, autoclavable 0.2μm air filter for gas inlet

* Gas Inlet (air) Includes mass flow controller: 2 vvm maximum according to the vessel capacity

* Gas Inlet (oxygen) Includes pure oxygen rotameter (manual flow control): 1 vvm maximum according to the vessel capacity

* Includes oxygen gas solenoid valve, with automatic pulsed time control

Air outlet / Exhaust

* Exhaust port with stainless steel condenser

* Includes re-useable, autoclavable 0.2μm air filter

* Includes automated adjustable gas outlet valve to adjust vessel back pressure

* Can control manually or automatically via software

Utility Requirement

Capacity: 100L  

Power: Three phase 220V or 380V (note: can be customized to local standard)

Air:

At least 7 bar

        200 L/min flow rate

        Dehumidified

        Oil-free

Peripheral factory water supply:
Cooling water (tap water, at least 15oC below working temperature, must be soft water);

Pressure at least 2 bar

Process water: RO Water

Plant steam: ≥ 2 bar; dry steam with no entrained condensate

Process steam: ≥ 2 bar; dry steam with no entrained condensate

Drain: In situ drain; ≥ 2"

* Customization on the SIP Fermentation system available upon request.